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mouse cytokine array panel a  (R&D Systems)


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    R&D Systems mouse cytokine array panel a
    <t>Cytokine</t> profiling showed significantly elevated levels of (A) CXCL10/IP-10 (1.37-fold increase; p < 0.0001, n = 3) and TIMP-1 (1.35-fold increase; p < 0.0001, n = 3) in the CD38-OE group compared to the CD38-WT group, and (B) ICAM-1, with a 1.15-fold increase compared to the CD38-WT group and a 1.34-fold increase compared to the control group (p < 0.0002, n = 3). No significant changes were observed in SDF-1/CXCL12 expression. (n = 3). These molecules were highlighted for their notable, yet relatively understudied, roles in GBM progression and tumor microenvironment modulation compared to other cytokines in the panel, which have more established functions in cancer biology. One-way ANOVA with Tukey’s post-hoc, *p < 0.0001, **p < 0.0002.
    Mouse Cytokine Array Panel A, supplied by R&D Systems, used in various techniques. Bioz Stars score: 96/100, based on 759 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/ary006+mouse+cytokine+array+kit/Proteome+Profiler+Mouse+Cytokine+Array+Kit%2C+Panel+A/pmc13090310-102-4-11
    Average 96 stars, based on 759 article reviews
    mouse cytokine array panel a - by Bioz Stars, 2026-10
    96/100 stars

    Images

    1) Product Images from "CD38 overexpression drives glioblastoma progression via L1CAM/ICAM1/JAK-STAT-Driven tumor microenvironment rewiring"

    Article Title: CD38 overexpression drives glioblastoma progression via L1CAM/ICAM1/JAK-STAT-Driven tumor microenvironment rewiring

    Journal: Translational Oncology

    doi: 10.1016/j.tranon.2026.102758

    Cytokine profiling showed significantly elevated levels of (A) CXCL10/IP-10 (1.37-fold increase; p < 0.0001, n = 3) and TIMP-1 (1.35-fold increase; p < 0.0001, n = 3) in the CD38-OE group compared to the CD38-WT group, and (B) ICAM-1, with a 1.15-fold increase compared to the CD38-WT group and a 1.34-fold increase compared to the control group (p < 0.0002, n = 3). No significant changes were observed in SDF-1/CXCL12 expression. (n = 3). These molecules were highlighted for their notable, yet relatively understudied, roles in GBM progression and tumor microenvironment modulation compared to other cytokines in the panel, which have more established functions in cancer biology. One-way ANOVA with Tukey’s post-hoc, *p < 0.0001, **p < 0.0002.
    Figure Legend Snippet: Cytokine profiling showed significantly elevated levels of (A) CXCL10/IP-10 (1.37-fold increase; p < 0.0001, n = 3) and TIMP-1 (1.35-fold increase; p < 0.0001, n = 3) in the CD38-OE group compared to the CD38-WT group, and (B) ICAM-1, with a 1.15-fold increase compared to the CD38-WT group and a 1.34-fold increase compared to the control group (p < 0.0002, n = 3). No significant changes were observed in SDF-1/CXCL12 expression. (n = 3). These molecules were highlighted for their notable, yet relatively understudied, roles in GBM progression and tumor microenvironment modulation compared to other cytokines in the panel, which have more established functions in cancer biology. One-way ANOVA with Tukey’s post-hoc, *p < 0.0001, **p < 0.0002.

    Techniques Used: Control, Expressing

    Related Articles

    Clinical Proteomics:

    Article Title: Impaired immune surveillance accelerates accumulation of senescent cells and aging
    Article Snippet: .. Relative levels of plasma cytokines and chemokines were assessed with an ARY006 mouse cytokine array kit (R&D Systems). ..

    Expressing:

    Article Title: Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions
    Article Snippet: .. To measure cytokine expression levels, pooled lysates from pancreata of ABT-737- and vehicle-treated mice, 3 per group, were tested with an ARY006 mouse cytokine array kit (R&D Systems) according to the manufacturer’s instructions. .. For mouse pancreas dissociation into single cell suspensions, pancreata were minced with scissors and incubated with trypsin-EDTA for 10 min at 37°C, followed by treatment with collagenase P (Sigma, 11213857001) 1 mg/mL for 20–30 min at 37°C, and then filtered through 70 and 40 μm filters.

    Article Title: Senolytic elimination of Cox2-expressing senescent cells inhibits the growth of premalignant pancreatic lesions.
    Article Snippet: .. To measure cytokine expression levels, pooled lysates from pancreata of ABT-737- and vehicle- treated mice, 3 per group, were tested with an ARY006 mouse cytokine array kit (R&D Systems) according to the manufacturer’s instructions. .. For mouse pancreas dissociation into single cell suspensions, pancreata were minced with scissors and incubated with trypsin- EDTA for 10 min at 37°C, followed by treatment with collagenase P (Sigma, 11213857001) 1 mg/mL for 20–30 min at 37°C, and then filtered through 70 and 40 μm filters.



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    Image Search Results


    Cytokine profiling showed significantly elevated levels of (A) CXCL10/IP-10 (1.37-fold increase; p < 0.0001, n = 3) and TIMP-1 (1.35-fold increase; p < 0.0001, n = 3) in the CD38-OE group compared to the CD38-WT group, and (B) ICAM-1, with a 1.15-fold increase compared to the CD38-WT group and a 1.34-fold increase compared to the control group (p < 0.0002, n = 3). No significant changes were observed in SDF-1/CXCL12 expression. (n = 3). These molecules were highlighted for their notable, yet relatively understudied, roles in GBM progression and tumor microenvironment modulation compared to other cytokines in the panel, which have more established functions in cancer biology. One-way ANOVA with Tukey’s post-hoc, *p < 0.0001, **p < 0.0002.

    Journal: Translational Oncology

    Article Title: CD38 overexpression drives glioblastoma progression via L1CAM/ICAM1/JAK-STAT-Driven tumor microenvironment rewiring

    doi: 10.1016/j.tranon.2026.102758

    Figure Lengend Snippet: Cytokine profiling showed significantly elevated levels of (A) CXCL10/IP-10 (1.37-fold increase; p < 0.0001, n = 3) and TIMP-1 (1.35-fold increase; p < 0.0001, n = 3) in the CD38-OE group compared to the CD38-WT group, and (B) ICAM-1, with a 1.15-fold increase compared to the CD38-WT group and a 1.34-fold increase compared to the control group (p < 0.0002, n = 3). No significant changes were observed in SDF-1/CXCL12 expression. (n = 3). These molecules were highlighted for their notable, yet relatively understudied, roles in GBM progression and tumor microenvironment modulation compared to other cytokines in the panel, which have more established functions in cancer biology. One-way ANOVA with Tukey’s post-hoc, *p < 0.0001, **p < 0.0002.

    Article Snippet: For cytokine profiling, the Mouse Cytokine Array Panel A (Catalog #ARY006, R&D Systems, USA) was used according to the manufacturer’s instructions (Supplementary Table).

    Techniques: Control, Expressing